Interferon administration vehicles

A - Human Necessities – 61 – K

Patent

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167/140, 167/159

A61K 9/06 (2006.01) A61K 9/08 (2006.01) A61K 38/21 (2006.01) A61K 47/00 (2006.01) A61K 47/10 (2006.01) A61K 47/38 (2006.01)

Patent

CA 1254832

ABSTRACT OF THE DISCLOSURE An interferon preparation to be administered topically is provided comprising: a) a therapeutically effective amount of one or more interferons; b) a vehicle base compatible with the interferon or interferons being administered; c) an effective amount of one or more protease inhibitors for the purpose of reducing the rate of decay of the biological activity of the interferon or interferons due to proteolytic agents; and d) an effective amount of one or more anti-microbial agents. In certain preferred embodiments of the invention, the vehicle base is prepared from a mixture of polyethylene glycols or includes hydroxyethyl cellulose as a thickening agent.

473606

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