C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 17/08 (2006.01) A61K 47/48 (2006.01) A61P 11/06 (2006.01) A61P 19/02 (2006.01) A61P 29/00 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) A61K 38/21 (2006.01) C07K 14/56 (2006.01)
Patent
CA 2698173
The present invention relates to interferon-.alpha.2b modified with Y-shaped branched polyethylene glycol (PEG) at a single Lys residue and the preparation thereof. The peglated IFN-.alpha.2b can be used for the preparation of a medicament for treating a disease, e.g. viral infections such as Hepatitis C.
L'invention concerne un interféron alpha 2B monomodifié par du polyéthylèneglycol à ramifications de type Y sur la position spécifique de la lysine, ainsi que le procédé de préparation associé. L'interféron alpha 2B PEG peut être utilisé dans l'élaboration d'une composition pharmaceutique destinée à traiter des maladies telles que des infections virales, type hépatite C, etc.
Liu Min
Luo Shihong
Sun Li
Wang Tiebing
Xiao Qingjiang
Biosteed Gene Expression Tech. Co. Ltd.
Blake Cassels & Graydon Llp
LandOfFree
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