C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/56 (2006.01) A61K 38/21 (2006.01) A61K 47/48 (2006.01) A61P 1/16 (2006.01) A61P 11/00 (2006.01) A61P 11/06 (2006.01) A61P 19/02 (2006.01) A61P 25/00 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) C07K 17/08 (2006.01)
Patent
CA 2698396
The present invention relates to interferon (IFN)-.alpha.2a modified at a specific Lys residue with Y-shaped branched polyethylene glycol (PEG) derivative and the preparation thereof, as well as the use of the prepared IFN-.alpha.2a modified by PEG at a single amino acid residue in medicines.
L'invention concerne un interféron alpha 2A modifié par du polyéthylèneglycol à ramifications de type Y sur le site particulier de la lysine, ainsi que son processus de synthèse et l'application dudit interféron alpha 2A PEG sur un seul site dans la préparation de médicaments.
Lei Lifang
Lin Song
Liu Bin
Liu Min
Sun Li
Biosteed Gene Expression Tech. Co. Ltd.
Blake Cassels & Graydon Llp
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