Interferon complex and pharmaceutical use thereof

A - Human Necessities – 61 – K

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Details

A61K 38/21 (2006.01) A61K 47/36 (2006.01) A61K 47/48 (2006.01) A61P 27/02 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2387205

A modified IFN obtained by modifying IFN so as to prolong the blood duration of IFN and make it to act specifically on tumor or eye tissue having neovasa. Namely, an interferon-dextran complex obtained by mixing interferon with dextran having a chelating ligand in the presence of a metal ion.

L'invention concerne un IFN modifié, de sorte que sa durée de vie dans le sang soit prolongée et qu'il agisse spécifiquement sur une tumeur ou un tissu de l'oeil présentant une croissance néovasculaire. Elle porte notamment sur un complexe interféron-dextrane, obtenu par mélange d'interféron et de dextrane possédant un ligand chélateur, en présence d'un ion métal.

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