Interferon for treatment of multiple sclerosis

Details Interferon for treatment of multiple sclerosis Interferon for treatment of multiple sclerosis

A - Human Necessities

61

K

A61K 38/21 (2006.01) A61P 25/00 (2006.01) C07K 14/555 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2413077

This invention relates to nucleic acids and polypeptide sequences, which code for an interferon-beta-2 ("IFN-.beta.2"). A pharmaceutical composition, which comprises a pharmaceutically acceptable excipient and a therapeutically effective amount of a human IFN-.beta.2 polypeptide, biologically-active fragment thereof, or biologically-active derivative thereof, is useful in treating multiple sclerosis in humans.

La présente invention concerne de nouveaux acides nucléiques et de nouvelles séquences polypeptidiques, qui codent un interféron-bêta 2 (<= IFN-.szlig.2 >=). Par ailleurs, cette invention concerne une composition pharmaceutique qui renferme un excipient acceptable d'un point de vue pharmaceutique et une dose efficace sur le plan thérapeutique d'un polypeptide IFN-.szlig.2 humain, ainsi qu'un fragment/dérivé biologiquement actif de celui-ci; cette composition étant utilisée dans le traitement de la sclérose en plaques chez les humains.

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