Interferon-gamma binding proteins

Details Interferon-gamma binding proteins Interferon-gamma binding proteins

C - Chemistry, Metallurgy

12

N

530/13, 167/103.

C12N 15/23 (2006.01) A61K 38/21 (2006.01) A61K 39/395 (2006.01) C07K 14/715 (2006.01) C07K 16/28 (2006.01) C12N 1/00 (2006.01) C12N 5/10 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2002833

The present invention relates to proteins having interferon-gamma (IFN-gamma) binding activity, to proteins substantially homologous therewith or fragments thereof, to DNA molecules, in particular cDNA molecules, encoding these proteins or fragments thereof, and to monocional antibodies to the human IFN-gamma receptor used for isolating said cDNA clones. The invention further relates to the cloning of said human IFN-gamma binding proteins and their production by recombinant DNA techniques and to pharmaceutical compositions comprising them.

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