Interferon gamma for the treatment of asthma

Details Interferon gamma for the treatment of asthma Interferon gamma for the treatment of asthma

A - Human Necessities

61

K

A61K 38/21 (2006.01) A61K 31/573 (2006.01) A61P 11/06 (2006.01)

Patent

CA 2387089

The invention describes for the first time the successful clinical application of interferon gamma (IFN-.gamma.) in human bronchial asthma therapy. The clinical data show unambiguously that continuous application of IFN-.gamma. in relatively low doses can be successfully used for long-term treatment of severe asthma bronchiale, especially for glucocorticoid-resistant asthma. The invention relates also to a combination therapy administering IFN-.gamma. and glucocorticoids, which alone are not or not sufficiently effective in asthma therapy.

L'invention concerne l'application clinique réussie et inédite de l'interféron gamma (IFN-.gamma.) dans la thérapie de l'asthme bronchique humain. Les données cliniques montrent sans ambiguïté que l'application continue d'IFN-.gamma. à doses relativement faibles permet de traiter à long terme l'asthme bronchique grave avec succès, spécialement l'asthme résistant aux glucocorticoïdes. L'invention concerne également une thérapie combinant IFN-.gamma. et glucocorticoïdes, qui, administrés seuls, ne sont pas ou pas assez efficaces dans la thérapie de l'asthme.

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