Interferon gel formulations

Details Interferon gel formulations Interferon gel formulations

A - Human Necessities

61

K

167/103.1

A61K 9/14 (2006.01) A61K 38/21 (2006.01) A61K 47/10 (2006.01) B65D 81/32 (2006.01)

Patent

CA 1218602

ABSTRACT A kit for formulating and dispensing an alpha-type interferon gel composition comprising a) a vial having an open end aseptically sealed and containing about 1 x 104 to 5 x 108 International Units of lyophilized alpha-type interferon formulation prepared from an alpha-type interferon having a specific activity of at least 5 x 10 International Units/mg. total protein; and b) a tube having flexible walls and sealing means at its open end and containing a dermatologically accep- table vehicle which contains a compatible preservative and a sufficient amount of polyoxyethylene polyoxypropylene block polymer for the vehicle to be liquid at about 15°C. and below and which together with the lyophilized alpha-type interferon gels at 15°C. and above; and methods for preparing said gel using said kit.

455490

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