C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
167/202, 195/1.2
C12P 19/34 (2006.01) C07H 21/00 (2006.01) C12N 9/12 (2006.01)
Patent
CA 1136562
ABSTRACT OF THE DISCLOSURE Double-stranded RNA synthesized using native human DNA as template is found to be an excellent inter- feron inducer with low toxicity in spite of homologous native to host cell. It is produced by reacting ATP, GTP, CTP and UTP with one another in the presence of a native human DNA as template by the catalytic action of an active RNA polymerase to form RNA and subjecting the resulting RNA to annealing by heating it at a temperature of 70° to 100°C and gradually cooling to room temperature or below to form double-stranded regions between their molecules.
332619
Arimura Hirofumi
Kitagawa Tsutomu
Nagai Masanori
Suyama Tadakazu
Yamauchi Takeshi
Fetherstonhaugh & Co.
The Green Cross Corporation
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