Interferon purification process

Details Interferon purification process Interferon purification process

C - Chemistry, Metallurgy

07

K

C07K 14/56 (2006.01) C07K 1/22 (2006.01)

Patent

CA 2062729

A process for the purification of a crude human leukocyte interferon, comprising the steps: a) applying a solution of said crude interferon onto an immuno-affinity adsorption column; b) eluting the adsorbed interferon from said column using a buffer solution; c) concentrating the eluate resulting from step b) with a thiocyanate solution by either precipitation or an exchange chromatography; and d) recovering the precipitated interferon obtained in step c).

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