Interferon regulatory factor-1/human estrogen receptor...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 5/10 (2006.01) A61K 31/7088 (2006.01) A61K 35/12 (2006.01) A61K 39/00 (2006.01) A61K 39/385 (2006.01) A61K 45/06 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01) C07K 14/47 (2006.01) C07K 14/72 (2006.01) C12N 15/62 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2439335

The invention relates to an interferon regulatory factor-1/human estrogen receptor fusion protein which is reversibly activatible by .beta.-estradiol and its use for treating carcinomas, particularly for treating hepatocellular carcinoma.

L'invention concerne une protéine du facteur régulateur de l'interféron-1/de fusion réceptrice d'oestrogène humain pouvant être activée de manière réversible par un .beta.-estradiol et son utilisation dans le traitement de carcinomes, notamment l'hépatocarcinome.

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