Interferon response in clinical samples (iris)

C - Chemistry – Metallurgy – 40 – B

Patent

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C40B 40/06 (2006.01) C12Q 1/68 (2006.01) C40B 30/04 (2006.01)

Patent

CA 2737486

The present invention relates to a specific set of genes useful for determining the efficacy of a treatment against multiple sclerosis (MS). Further, the invention provides an array of these genes useful for evaluating efficacy of a MS treatment. Also provided are methods for evaluating efficacy of an MS treatment and a method for detecting neutralizing antibodies in patient response to interferon.beta.-1B treatment of MS.

La présente invention porte sur un ensemble spécifique de gènes utiles pour déterminer l'efficacité d'un traitement contre la sclérose en plaques (MS). De plus, l'invention concerne un réseau de ces gènes utiles pour évaluer l'efficacité d'un traitement contre la MS. L'invention concerne également des procédés d'évaluation de l'efficacité d'un traitement contre la MS et un procédé de détection des anticorps neutralisants dans une réponse d'un patient à un traitement par interféron ß-1B contre la MS.

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