Interleukin-1 homolog zil1a7

Details Interleukin-1 homolog zil1a7 Interleukin-1 homolog zil1a7

C - Chemistry, Metallurgy

12

N

C12N 15/25 (2006.01) A61K 38/20 (2006.01) C07K 14/54 (2006.01) C07K 14/545 (2006.01) C07K 16/18 (2006.01) C07K 16/24 (2006.01) C07K 19/00 (2006.01) C12N 15/63 (2006.01) C12P 21/00 (2006.01) C12P 21/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2443913

Homologs of interleukin-1, materials and methods for making them, compositions comprising them, and methods of using them are disclosed. The homologs are proteins comprising a sequence of amino acid residues as shown in SEQ ID NO:2 from residue 32 through residue 166. The proteins have inflammation modulating activity and are useful within related research and therapeutic applications.

L'invention concerne des homologues de l'interleukine-1, leurs matières et méthodes d'élaboration, des compositions les contenant et leurs méthodes d'utilisation. Ces homologues sont des protéines renfermant une séquence de résidus d'acides aminés présentée dans SEQ ID NO:2 à partir du résidu 32 à travers le résidu 166. Ces protéines ont une activité modulatrice des inflammations et sont utilisées dans des applications de recherche et de thérapie.

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