Interleukin-1 receptor antagonist beta (il-1ra.beta.)

Details Interleukin-1 receptor antagonist beta (il-1ra.beta.) Interleukin-1 receptor antagonist beta (il-1ra.beta.)

C - Chemistry, Metallurgy

12

N

C12N 15/25 (2006.01) A61K 31/70 (2006.01) A61K 38/20 (2006.01) A61K 48/00 (2006.01) C07K 14/54 (2006.01) C07K 14/545 (2006.01) C07K 16/24 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2232812

IL-1ra beta polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing IL-1ra beta polypeptides and polynucleotides in the design of protocols for the treatment of chronic and acute inflammation, septicemia, cancer, anemia, arthritis, inflammatory bowel disease, graft vs. host disease, autoimmunity, stroke, cardiac ischemia, acute respiratory disease syndrome (ARDS), psoriasis, restenosis, traumatic brain injury, AIDS, cancer, anemia, cachexia, among others, and diagnostic assays for such conditions.

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