C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/24 (2006.01) A01K 67/027 (2006.01) A61K 9/50 (2006.01) A61K 38/19 (2006.01) C07K 14/54 (2006.01) C07K 14/545 (2006.01) C07K 16/24 (2006.01) C07K 16/46 (2006.01) C12N 5/10 (2006.01) C12N 5/16 (2006.01) C12N 15/62 (2006.01) C12N 15/63 (2006.01) C12N 15/74 (2006.01) C12N 15/79 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2393661
The present invention provides novel Interleukin-1 Receptor Antagonist-Like (IL-1ra-L) polypeptides and nucleic acid molecules encoding the same. The invention also provides selective binding agents, vectors, host cells, and methods for producing (IL-1ra-L) polypeptides. The invention further provides pharmaceutical compositions and methods for the diagnosis, treatment, amelioration, and/or prevention of diseases, disorders, and conditions associated with IL-1ra-L polypeptides.
La présente invention concerne des nouveaux polypeptides du type antagonistes du récepteur de l'interleukine 1 (IL-1ra-L) et des molécules d'acide nucléique codant pour ces polypeptides. L'invention concerne également des agents de liaison sélective, des vecteurs, des cellules hôtes et des méthodes destinées à la production de polypeptides IL-1ra-L. Elle se rapporte en outre à des compositions pharmaceutiques et à des méthodes destinées au diagnostic, au traitement, à l'amélioration et/ou à la prévention de maladies, de troubles et d'états pathologiques associés aux polypeptides IL-1ra-L.
Jing Shuqian
Luethy Roland
Welcher Andrew A.
Amgen Inc.
Gowling Lafleur Henderson Llp
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