Interleukin 17 receptor-like protein

Details Interleukin 17 receptor-like protein Interleukin 17 receptor-like protein

C - Chemistry, Metallurgy

12

N

C12N 15/24 (2006.01) C07K 14/705 (2006.01) C07K 14/715 (2006.01) C07K 16/24 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12N 5/16 (2006.01) C12N 15/12 (2006.01) C12N 15/63 (2006.01) C12N 15/64 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2363024

The present invention relates to a novel IL17RLP protein which is a member of the interleukin (IL)-17 receptor family. In particular, isolated nucleic acid molecules are provided encoding the human IL17RLP protein. IL17RLP polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of IL17RLP activity. Also provided are diagnostic methods for detecting immune system-related disorders and therapeutic methods for treating, diagnosing, detecting, and/or preventing immune system-related disorders.

L'invention concerne une nouvelle protéine IL17RLP qui fait partie de la famille des récepteurs de l'interleukine (IL)-17. L'invention concerne plus particulièrement des molécules d'acides nucléiques isolées codant pour la protéine IL17RLP humaine. L'invention concerne aussi des polypeptides IL17RLP, des vecteurs, des cellules hôtes et des techniques recombinantes permettant l'obtention de ceux-ci. L'invention concerne encore des procédés de criblage permettant d'identifier des agonistes et des antagonistes de l'activité de l'IL17RLP, des méthodes diagnostiques permettant de détecter des troubles liés au système immunitaire et des méthodes thérapeutiques permettant de traiter, de diagnostiquer, de détecter et/ou de prévenir des troubles liés au système immunitaire.

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