Interleukin-18 mutants, their production and use

Details Interleukin-18 mutants, their production and use Interleukin-18 mutants, their production and use

C - Chemistry, Metallurgy

12

N

C12N 15/24 (2006.01) A61K 38/20 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) C07K 14/54 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2438851

The invention provides mutants of IL-18 with lower affinity to IL-18BP than the wild type IL-18 molecule.

L'invention concerne des mutants de IL-18 qui présentent moins d'affinité avec IL-18BP qu'avec la molécule IL-18 de type sauvage.

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