Interleukin-4 stimulated t lymphocyte cell death

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/00 (2006.01) A61K 38/20 (2006.01) A61K 39/35 (2006.01) A61P 37/02 (2006.01) A61P 37/08 (2006.01) C12N 1/06 (2006.01) C12N 5/00 (2006.01) A61K 35/12 (2006.01)

Patent

CA 2140878

This invention discloses a method for the treatment or prevention of autoimmune diseases, allergic or atopic disorders and graft rejection. Specifically, it provides a means of killing a specific subpopulation of T lymphocytes while leaving the majority of other T lymphocytes in the population unaffected. The subpopulation of T lymphocytes are killed by repeatedly challenging the population with an antigen in conjuction with administration of interleukin-4.

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