Interleukin-8 labelled via one or more site specifically...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/54 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2625993

Interleukin-8, or an analog or derivative thereof, labelled via one or more hydrazinonicotinamide (HYNIC) moieties site-specifically conjugated to one or 5 more internal lysines and/or an N-terminal amino acid, for use in diagnosis of infection and inflammation.

L'invention concerne une interleukine 8, ou un analogue ou un dérivé de celle-ci, marquée au moyen d'une ou plusieurs fractions hydrazinonicotinamide (HYNIC) conjuguées de manière régiospécifique à une ou plusieurs lysines internes et/ou à un acide aminé N-terminal, en vue d'une utilisation dans le diagnostic d'une infection et d'une inflammation.

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