Intermediate isoxazoles

C - Chemistry – Metallurgy – 07 – J

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260/10

C07J 71/00 (2006.01)

Patent

CA 1125278

A B S T R A C T Intermediate isoxazoles are used in the preparation of 2.alpha.-cyano 3-oxosteroids having a 4.alpha.,5.alpha.-epoxy group and being alkylated in the 4- and/or 6-position. The intermedi- ates are prepared by epoxidizing the double bond in a corre sponding unsaturated isoxazol. Some species of the present intermediates are useful in disrupting pregnancy in female mammals.

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