C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
260/10
C07J 71/00 (2006.01)
Patent
CA 1125278
A B S T R A C T Intermediate isoxazoles are used in the preparation of 2.alpha.-cyano 3-oxosteroids having a 4.alpha.,5.alpha.-epoxy group and being alkylated in the 4- and/or 6-position. The intermedi- ates are prepared by epoxidizing the double bond in a corre sponding unsaturated isoxazol. Some species of the present intermediates are useful in disrupting pregnancy in female mammals.
383967
Smart & Biggar
Sterling Drug Inc.
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