Intermediate used for the preparation of deferoxamine

Details Intermediate used for the preparation of deferoxamine Intermediate used for the preparation of deferoxamine

C - Chemistry, Metallurgy

07

C

C07C 271/20 (2006.01) C07C 259/06 (2006.01)

Patent

CA 2083149

A method for preparing deferoxamine and a composition of formula (I): X-Ph-CH2- O-C(O)-NH-(CH2)4-CH = NOR, wherein X is a C1-C4 alkyl, -O(C1-C4 alkyl), a halogen or hydrogen; R is X-Ph- CH2- or hydrogen for preparing deferoxa- mine. In one embodiment X and R are hydrogen. The intermediate formula (I), has the advantage of being prepared in few- er and more efficient steps from readily available materials than conventional means for preparing deferoxamine.

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