Intermediates and methods for the synthesis of...

Details Intermediates and methods for the synthesis of... Intermediates and methods for the synthesis of...

C - Chemistry, Metallurgy

07

D

C07D 231/54 (2006.01) C07D 405/12 (2006.01) C07F 7/10 (2006.01)

Patent

CA 2162018

This invention relates to compounds, including 5-chloro 2-[2-[[(4-methylphenyl)sulfonyl]oxy]ethyl]-7-[2,4,6- trimethylphenyl)methoxy]anthra[1,9-cd]pyrazol(2H)-one and analogs thereof, which are useful as intermediates for the synthesis of anthrapyrazolone anticancer agents, including losoxantrone. This invention also relates to methods for the synthesis of anthrapyrazolone anticancer agents, including losoxantrone.

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