Intermediates and processes for 6-alpha-hydroxymethyl...

Details Intermediates and processes for 6-alpha-hydroxymethyl... Intermediates and processes for 6-alpha-hydroxymethyl...

C - Chemistry, Metallurgy

07

D

260/357.3, 260/2

C07D 309/30 (2006.01) C07D 407/00 (2006.01) C07D 407/06 (2006.01) C07F 7/18 (2006.01)

Patent

CA 1307268

0107/MW3 1770 TITLE OF INVENTION INTERMEDIATES AND PROCESSES FOR 6-.alpha.-HYDROXYMETHYL HMG CoA REDUCTASE INHIBITORS ABSTRACT OF THE DISCLOSURE This invention discloses intermediates and a process for the preparation of 6-desmethyl-6-.alpha.- hydroxymethyl derivatives of lovastatin and analogs thereof at the 8-acyl side chain. The intermediates of the present invention are of the general formula: Image

592085

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