Intermediates for polycyclic quinonoid antibiotics

Details Intermediates for polycyclic quinonoid antibiotics Intermediates for polycyclic quinonoid antibiotics

C - Chemistry, Metallurgy

07

C

260/208

C07C 237/26 (2006.01) C07C 46/00 (2006.01) C07C 46/02 (2006.01) C07C 46/06 (2006.01)

Patent

CA 1097343

RC 3.0-136 INTERMEDIATES FOR POLYCYCLIC QUINONOID ANTIBIOTICS ANDREW S. KENDE YUH-GENG TSAY JOHN E. MILLS ABSTRACT OF THE DISCLOSURE There is provided a novel method of synthesizing certain tetracyclic quinones. In particular, there is provided a novel route to the synthesis of certain analogs of (?)-7-deoxydauno- mycinone which includes the provision of novel tri- and tetracyclic quinone intermediates. The products of the synthetic route provided herein may be converted into compounds of known anti-neo- plastic activity.

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