Intermediates for preparing 3-propenylcephem derivatives

C - Chemistry – Metallurgy – 07 – D

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260/308.3

C07D 285/08 (2006.01) C07F 7/10 (2006.01)

Patent

CA 1305487

ABSTRACT A 3-propenylcephem derivative of the following formula: Image wherein R1 represents a fluoro-substituted lower alkyl group or a cyano-substituted lower alkyl group, and A represents a cyclic or an acylic ammonio group, or a pharmaceutically acceptable salt thereof, exhibiting excellent anti-bacterial activities against both Gram-positive bacteria and Gram-negative bacteria; Process for the preparation thereof; Anti-bacterial composition; Intermediate for the 3-propenylcephem derivative; and Process for the preparation of the intermediate.

615965

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