Intermediates for preparing neuraminidase inhibitor conjugates

Details Intermediates for preparing neuraminidase inhibitor conjugates Intermediates for preparing neuraminidase inhibitor conjugates

C - Chemistry, Metallurgy

07

D

C07D 407/06 (2006.01) C07D 309/28 (2006.01) C07D 407/14 (2006.01)

Patent

CA 2456239

Compounds of formula (I), methods for their preparation and their use in the manufacture of neuraminidase inhibitor conjugates. Wherein R represents as carboxylic acid protecting group; P1 and P2 can be the same or different and are selected from amine protecting groups; P3 represents a protecting group for 1, 2 diols; and LG represents a leaving group.

L'invention concerne des composés de formule (I), des procédés de préparation associés et leur utilisation dans la production de conjugués inhibiteurs de la neuraminidase. Formule (I), dans laquelle R représente un groupe protecteur de l'acide carboxylique, P¿1? et P¿2? sont identiques ou différents et sélectionnés dans des groupes protecteur d'amine, P¿3? signifie un groupe protecteur pour des 1,2 diols, et LG désigne un groupe partant.

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