Intermediates for synthesis of vinblastine and its...

Details Intermediates for synthesis of vinblastine and its... Intermediates for synthesis of vinblastine and its...

C - Chemistry, Metallurgy

07

D

C07D 405/12 (2006.01) C07D 209/18 (2006.01) C07D 215/18 (2006.01) C07D 215/20 (2006.01)

Patent

CA 2416454

Intermediates A, which are important in the whole synthesis of vindoline; and a method of synthesizing intermediates respectively represented by the general formulae B and C. By the method, the target intermediates are effectively synthesized with satisfactory reproducibility. This synthesis method is especially suitable for mass production. General formula A General formula B General formula C

L'invention porte sur les intermédiaires A importants pour la synthèse totale de la vindoline et sur un procédé de synthèse les intermédiaires de formules respective B et C. Ce procédé, qui permet de synthétiser les intermédiaires cibles efficacement et de manière reproductible est spécialement adapté à la production en masse. Formule générale A Formule générale B Formule générale C

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