Intermediates for the preparation of analogs of halichondrin b

C - Chemistry – Metallurgy – 07 – F

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C07F 7/18 (2006.01) C07D 307/20 (2006.01) C07D 307/28 (2006.01) C07D 493/10 (2006.01) C07D 493/20 (2006.01) C07D 493/22 (2006.01)

Patent

CA 2567984

The present invention provides macrocyclic compounds, synthesis of the same and intermediates thereto. Such compounds, and compositions thereof, are useful for treating or preventing proliferative disorders Formula (F-4).

Des composés macrocycliques, la synthèse de ceux-ci et de leurs intermédiaires. De tels composés, et leurs compositions, servent à traiter ou éviter les troubles prolifératifs de formule F4.

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