Intermediates for the preparation of prostaglandin analogues

Details Intermediates for the preparation of prostaglandin analogues Intermediates for the preparation of prostaglandin analogues

C - Chemistry, Metallurgy

07

D

260/235.01, 260/

C07D 309/12 (2006.01) C07D 307/20 (2006.01) C07C 177/00 (1980.01)

Patent

CA 1151163

ABSTRACT Compounds of the formula Image (wherein R1 represents a hydrogen atom or a straight- or branched chain alkyl group containing from 1 to 4 carbon atoms, the grouping -R2-R3 represents a 2- methylhexyl group, R4 represents a tetrahydropyran-2-yl or tetrahydrofuran-2-yl group, each such group being unsubstituted or substituted by at least one alkyl group, or represents a 1-ethoxyethyl group, and tbe dotted line attached to the C-11 and C-15 carbon atoms represents .alpha.-configuration) are intermediates useful in the preparation of prostaglandin analogues which possess useful pharma- cological properties.

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