Intermediates for the preparation of pyrrolidine derivatives

C - Chemistry – Metallurgy – 07 – D

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260/487.2, 260/3

C07D 309/12 (2006.01) C07C 103/48 (1985.01)

Patent

CA 1268472

ABSTRACT OF THE DISCLOSURE: A process for preparing compounds (1) Image (1) where Y is NR1R2 or OR, R1 and R2 are hydrogen or C1-3 alkyl, and R is C1-3 alkyl, comprises protecting the hydroxy group of a compound (2) Image (2) cyclising the product under basic conditions and removing the protecting group. The compounds (2) with or without the protecting group are useful intermediates in the above process. The compounds (1) themselves, are useful psycho- tropic compounds which restore cognitive function in animals and man damaged by various pathologies.

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