Intermediates for the synthesis of ( )-4-demethoxydaunorubicin

Details Intermediates for the synthesis of ( )-4-demethoxydaunorubicin Intermediates for the synthesis of ( )-4-demethoxydaunorubicin

C - Chemistry, Metallurgy

07

F

260/208

C07F 7/08 (2006.01)

Patent

CA 1125284

Case 2135 Pappo & Garland INTERMEDIATES FOR THE SYNTHESIS OF 4-DEMETHOXYDAUNORUBICIN Abstract of the Disclosure The present invention encompasses novel inter- mediates having the following structural formulas: (+) Image wherein X is hydrogen, methoxy, or hydroxy; (+) Image wherein X is hydrogen, methoxy, or hydroxy; and Image wherein X is hydrogen, methoxy, or hydroxy. Compounds of the present invention are useful in synthesizing (+)-4-demethoxydaunorubicin, daunorubicin, adriamycin, and carminomycin which are potent antitumor agents.

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