Intermediates in the formation of the calicheamicin and...

Details Intermediates in the formation of the calicheamicin and... Intermediates in the formation of the calicheamicin and...

C - Chemistry, Metallurgy

07

F

C07F 7/10 (2006.01) C07D 263/24 (2006.01) C07D 309/30 (2006.01) C07D 491/04 (2006.01) C07D 493/04 (2006.01) C07D 521/00 (2006.01) C07F 7/18 (2006.01) C07H 17/04 (2006.01) C07H 23/00 (2006.01)

Patent

CA 2082152

Intermediates useful in preparing the calicheamicin and esperamicin oligosaccharides, and particularly the sulfur- and O-substituted hydroxylamine-containing B ring of both oligosaccharides, are disclosed as are methods of making and using the same, including the preparation of chimeric antibiotics using the same.

On divulgue des intermédiaires utiles dans la préparation des oligosaccharides calichéamicine et espéramicine, et particulièrement les noyaux B contenant une hydroxylamine substituée par le soufre et l'oxygène des deux oligosaccharides, de même que des méthodes pour les fabriquer et les utiliser, y compris la préparation d'antibiotiques chimères avec ces derniers.

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