Intermediates useful in the preparation of hmg-coa reductase...

Details Intermediates useful in the preparation of hmg-coa reductase... Intermediates useful in the preparation of hmg-coa reductase...

C - Chemistry, Metallurgy

07

C

260/476, 260/447

C07C 69/708 (2006.01) C07C 69/78 (2006.01) C07D 303/40 (2006.01) C07D 309/30 (2006.01) C07F 7/18 (2006.01)

Patent

CA 1273352

17194 ABSTRACT OF THE DISCLOSURE There is provided compounds having the follow- ing formula: Image wherein Y is chloro or bromo; Pr is a protecting group selected from benzoyl, acetyl, triphenylsilyl or t-butyldiphenylsilyl; R5 is C1-5 alkyl or benzyl; and R7 is C1-5 alkyl, benzyl, C2-5 alkoxyalkyl or C3-6 alkoxyalkoxyalkyl. These compounds are useful as intermediates for the preparation of HMG-CoA reductase inhibitors.

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