C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/04 (2006.01) C07D 401/14 (2006.01) C07D 405/14 (2006.01) C07D 413/14 (2006.01)
Patent
CA 2611219
The invention is directed to alkylquinoline and alkylquinazoline compounds of Formula C: wherein R1, R2, R99, and X are as defined herein, the use of such compounds in the sysnthesis of protein tyrosine kinase inhibitors, particularly inhibitors of FLT3 and/or c-kit and/or TrkB.
L'invention concerne des composés d'alkylquinoline et d'alkylquinazoline de formule C dans laquelle: R1, R2, R99, et X sont tels que définis dans la description, l'utilisation de tels composés dans la synthèse d'inhibiteurs de protéine tyrosine kinase, notamment des inhibiteurs de FLT3 et/ou c-kit et/ou TrkB.
Baindur Nand
Gaul Michael David
Kreutter Kevin Douglas
Xu Guozhang
Janssen Pharmaceutica N.v.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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