Internalisation of virus into cells

Details Internalisation of virus into cells Internalisation of virus into cells

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A01K 67/00 (2006.01) A61K 45/00 (2006.01) A61P 31/12 (2006.01) C07K 14/705 (2006.01) C07K 14/72 (2006.01) C07K 16/08 (2006.01) C07K 16/10 (2006.01) C07K 19/00 (2006.01) C12N 15/12 (2006.01) C12N 15/13 (2006.01) C12N 15/63 (2006.01) C12Q 1/00 (2006.01) C12Q 1/02 (2006.01) C12Q 1/70 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2448092

A chimeric transmembrane protein which promotes viral entry into cells comprises: (i) an extracellular domain capable of binding a virus; and (ii) an intracellular internalisation signal.

L'invention concerne une protéine transmembranaire chimère qui stimule la pénétration des virus dans les cellules. Cette protéine comprend: (I) un site extracellulaire capable de fixer le virus; et (II) un signal d'internalisation intracellulaire.

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