A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/17 (2006.01) A61K 31/70 (2006.01) A61K 38/03 (2006.01) A61K 38/04 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 14/82 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2195533
Compounds for use in interfering with the binding between p53 and MDM2 or a protein having a p53 binding site analogous to that of MDM2, the compound being selected from the group consisting of a peptide having up to twenty- eight amino acids which is able to disrupt or prevent binding between p53 and MDM2, or a functional peptide analogue thereof. Methods for detecting such compounds and their application in the diagnosis and treatment of tumours is also described and claimed.
Des composés sont utilisés pour interférer avec la liaison entre la protéine p53 et MDM2 ou une protéine possédant un site de liaison sur la p53 analogue à celui de la MDM2, le composé étant sélectionné dans le groupe constitué d'un peptide possédant jusqu'à 28 acides aminés qui peut interrompre ou empêcher la liaison entre p53 et MDM2, ou un analogue peptidique fonctionnel de ces protéines. Des procédés de détection de ces composés et leur application dans le diagnostic et le traitement de tumeurs sont également décrits et revendiqués.
Lane David Philip
Picksley Steven Michael
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
University Of Dundee
LandOfFree
Interruption of binding of mdm2 and p53 protein and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Interruption of binding of mdm2 and p53 protein and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Interruption of binding of mdm2 and p53 protein and... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1362320