A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/465 (2006.01) A61K 9/52 (2006.01) A61K 47/32 (2006.01) A61P 25/28 (2006.01) A61P 25/34 (2006.01) A61P 29/00 (2006.01)
Patent
CA 2260909
Nicotine is absorbed systemically from the intestine in therapeutic amounts for the treatment of nicotine responsive conditions, particularly in-flammatory skin conditions, Alzheimer's disease, schizophrenia, Parkinson's disease, Tourette's syn-drome, depression and to assist in the cessation of smoking. The nicotine is ideally delivered for ab-sorption from the colon as a nicotine-polyacrylate complex in a sustained and delayed released enteric coated capsule. In this way, the high peak plasma levels, which normally give rise to side-effects as-sociated with nicotine are reduced.
La nicotine est absorbée de manière systémique au niveau de l'intestin, dans des quantités thérapeutiques permettant de traiter des états répondant à la nicotine, en particulier, des états inflammatoires de la peau, la maladie d'Alzheimer, la schizophrénie, la maladie de parkinson, le syndrome de Tourette, la dépression et comme aide à l'arrêt de la tabagie. La nicotine est administrée de manière idéale en vue de son absorption au niveau du colon sous forme d'un complexe nicotine-polyacrylate dans une capsule à délitage entérique à libération prolongée et effet retard. Ainsi, cela permet de réduire taux plasmatiques maximaux, qui normalement se traduisent par des effets secondaires associés à la nicotine.
Evans Brian Kenneth
Rhodes John
Rhodes Peter
Sandborn William Jeffery
Mayo Foundation For Medical Education And Research
Sim & Mcburney
LandOfFree
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