Intestinal epithelial glucose sensor

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/071 (2010.01) A61K 38/17 (2006.01) C12Q 1/02 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2577632

The present invention relates to a mammalian intestinal epithelial glucose sensor, more specifically to a human intestinal epithelial glucose sensor. The invention relates further to the use of this sensor to modulate or monitor intestinal carbohydrate uptake and metabolism and to the use of ligands and/or inhibitors and/or activators of this sensor to treat or prevent diseases such as diabetes and obesity, and to provide nutritional aids for the elderly, infants and athletes.

La présente invention a pour objet un détecteur de glucose épithélial intestinal adapté aux mammifères, et plus particulièrement un détecteur de glucose épithélial intestinal humain. La présente invention a également pour objet l~emploi de ce détecteur pour moduler ou réguler l~apport et le métabolisme des hydrates de carbone au niveau de l~intestin, ainsi que l'utilisation de ligands, et/ou d'inhibiteurs et/ou d'activants de ce détecteur dans le but de traiter ou de prévenir des maladies telles que le diabète et l~obésité, et de fournir des compléments alimentaires aux personnes âgées, aux nourrissons et aux athlètes.

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