Intra-cancer-cell nuclease activator

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/48 (2006.01) A61K 9/127 (2006.01) A61K 31/70 (2006.01) A61K 31/713 (2006.01) C07H 13/06 (2006.01) C07H 21/02 (2006.01)

Patent

CA 2306085

A drug efficacious for cancer therapy and a novel drug containing a double- stranded RNA such as poly(I).poly(C). Specifically, an intra-cancer-cell nuclease activator containing 2-O-(2-diethylaminoethyl)-carbamoyl-1,3-O- dioleylglycerol and a composite comprising a carrier prepared from a phospholipid as an essential component and poly(I).poly(C) or mismatched poly(I).poly(C).

Cette invention se rapporte à un médicament efficace dans le traitement du cancer et à un nouveau médicament contenant un ARN à double brin, tel que poly(I).poly(C). Cette invention se rapporte spécifiquement à un activateur de nucléase de cellules intracancéreuses, contenant du 2-O-(2-diéthylaminoéthyl)-carbamoyl-1,3-O-dioleylglycérol et un composite contenant un vecteur préparé à partir d'un phospholipide comme constituant essentiel et poly(I).poly(C) ou poly(I).poly(C) non apparié.

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