Intrabead screening methods and compositions

Details Intrabead screening methods and compositions Intrabead screening methods and compositions

G - Physics

01

N

G01N 33/543 (2006.01) B01J 19/00 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2362054

The invention relates to the use of porous beads to screen candidate bioactive agents for the ability to interact or effect a target substance. The screen is performed in the interior and exterior surface of the bead, allowing extremely small sample sizes and concentration of reagents, while retarding evaporation.

Cette invention a trait à l'utilisation de billes poreuses pour le criblage d'agents candidats bioactifs et ce, afin de déterminer leur aptitude à interagir avec une substance cible ou à avoir un effet sur celle-ci. Le criblage se fait au niveau des surfaces de la bille, interne et externe, ce qui permet d'avoir des échantillons de taille extrêmement réduite et en teneur en réactif également extrêmement réduite, tout en retardant l'évaporation.

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