Intrabuccally disintegrating preparation and production thereof

Details Intrabuccally disintegrating preparation and production thereof Intrabuccally disintegrating preparation and production thereof

A - Human Necessities

61

K

A61K 47/36 (2006.01) A61K 9/00 (2006.01) A61K 9/20 (2006.01) A61K 47/26 (2006.01)

Patent

CA 2126669

solid preparation soluble in the buccal cavity, which is composed of a sugar comprising lactose and/or mannitol and 0.1 - 1.2 w/w%, based on the sugar, of agar and an active ingredient and has a density, of 400 -to 1,000 mg/ml and such a strength as to withstand the handling in the manufacture thereof. It has such a sufficient practical solubility in the buccal cavity that even the aged or children having difficulty in swallowing a solid preparation, such as a tablet, can take it. It has an exceedingly high strength as compared with conventional open matrix structures and hence can withstand satisfactorily carrying and PTP packaging.

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