Intracellular antigen found in subpopulation of cd8+t...

Details Intracellular antigen found in subpopulation of cd8+t... Intracellular antigen found in subpopulation of cd8+t...

C - Chemistry, Metallurgy

12

N

530/13, 167/37,

C12N 15/12 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) C12P 21/08 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2033644

Abstract of the Disclosure A 15 kd protein antigen is associated with cytoplasmic granules in cytolytic T lymphocytes and natural killer cells. Monoclonal antibodies immunologically reactive with the 15 kd protein and nucleic acid probes encoding polypeptides that are immunologically cross-reactive with the 15 kd protein can be used, e.g., to identify cytolytic lymphocytes in a sample. Cloned cDNA encoding the antigen can be used to produce the antigen.

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