A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/127 (2006.01) F02B 75/02 (2006.01)
Patent
CA 2223788
An improved liposome and related methods for using the liposome to facilitate the delivery of an extracellular agent to the cytoplasm of a target cell are provided. The improved liposomes include a phagosomal membrane permeabilizer, such as a hemolysin.
L'invention concerne un liposome amélioré et les procédés connexes d'utilisation dudit liposome pour faciliter l'administration d'un agent extracellulaire au cytoplasme d'une cellule cible. Ces liposomes améliorés contiennent un agent, tel qu'une hémolysine, qui permet de perméabiliser la membrane du phagosome.
Lee Kyung-Dall
Portnoy Daniel A.
Swanson Joel A.
President And Fellows Of Harvard College
Smart & Biggar
University Of Pennsylvania
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