C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/63 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C12N 15/00 (2006.01) C12N 15/85 (2006.01) C12N 15/86 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2298410
The present invention relates, in general, to myocardial hypertrophy and, in particular, to agents that inhibit cardiac Gq-coupled receptor signaling and to methods of inhibiting myocardial hypertrophy using same.
La présente invention concerne, d'une manière générale, l'hypertrophie myocardique et, en particulier, des agents inhibants la signalisation du récepteur cardiaque couplé aux protéines Gq, ainsi que des méthodes d'inhibition de l'hypertrophie myocardique les utilisant.
Akhter Shahab A.
Koch Walter J.
Lefkowitz Robert J.
Luttrell Louis M.
Rockman Howard
Duke University
Goudreau Gage Dubuc
University Of North Carolina At Chapel Hill
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