Intracellular signaling molecules

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A01K 67/00 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) A61K 49/00 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12P 21/02 (2006.01) C12P 21/08 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2458645

Various embodiments of the invention provide human intracellular signaling molecules (INTSIG) and polynucleotides which identify and encode INTSIG. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of INTSIG.

Plusieurs modes de réalisation de l'invention concernent des molécules humaines de signalisation intracellulaire (INTSIG) et des polynucléotides identifiant et codant les molécules INTSIG. Des modes de réalisation de l'invention concernent également des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes. Enfin d'autres modes de réalisation de l'invention concernent des méthodes de diagnostic, de traitement ou de prévention de troubles associés à une expression aberrante des molécules INTSIG.

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