Intradermal cellular delivery using narrow gauge micro-cannula

Details Intradermal cellular delivery using narrow gauge micro-cannula Intradermal cellular delivery using narrow gauge micro-cannula

A - Human Necessities

61

M

A61M 37/00 (2006.01) A61M 5/00 (2006.01) A61K 35/12 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2513029

A method for delivering cells into a subject by administering cells into the intradermal space of the skin of the subject by a microneedle. The cells are associated with cellular based therapeutics and vaccines and delivered by perpendicular insertion of the microneedle. The microneedle is a hollow needle having an exposed height of between about 0 and 1 mm, a total length of between about 0.3 mm to 2.5 mm, and a size of equal to or less than 30 gauge. An array of microneedles can also be used.

L'invention concerne une méthode pour administrer des cellules à un sujet en les introduisant par voie intradermique au moyen d'une micro-aiguille. Les cellules sont associées à des agents thérapeutiques à base cellulaire et à des vaccins à base cellulaire et elles sont administrées par insertion perpendiculaire d'une micro-aiguille dans la peau. Cette micro-aiguille est une aiguille creuse présentant une hauteur apparente d'environ 0 à 1 mm, une longueur totale variant entre 0.3 mm et 2.5 mm environ et un calibre inférieur ou égal à 30, toute une série de micro-aiguilles pouvant être utilisée.

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