Intraluminal device with controlled biodegradation

Details Intraluminal device with controlled biodegradation Intraluminal device with controlled biodegradation

A - Human Necessities

61

L

A61L 31/10 (2006.01) A61L 31/14 (2006.01)

Patent

CA 2757268

An intraluminal device with controlled biodegradation is provided. The intraluminal device comprises a biodegradable tubular main body. An outer photodegradable layer is disposed over at least a portion of the intraluminal device. The photodegradable outer layer is chemically inert to the body fluids of the implanted region, thereby preventing premature biodegradation of the stent. Degradation of the outer photodegradable layer after a predetermined time occurs by irradiating the layer with UV light waves. After removal of the outer photodegradable layer, the tubular main body becomes exposed to the in vivo environment, thereby allowing biodegradation of the tubular main body.

L'invention porte sur un dispositif intraluminal avec biodégradation contrôlée. Le dispositif intraluminal comprend un corps principal tubulaire biodégradable. Une couche photodégradable externe est disposée sur au moins une partie du dispositif intraluminal. La couche photodégradable externe est chimiquement inerte vis-à-vis des fluides corporels de la région implantée, de façon à empêcher ainsi une biodégradation prématurée du stent. Une dégradation de la couche photodégradable externe après un temps prédéterminé se produit par irradiation de la couche avec des ondes lumineuses ultraviolettes. Après le retrait de la couche photodégradable externe, le corps principal tubulaire devient exposé à l'environnement in vivo, de façon à permettre ainsi la biodégradation du corps principal tubulaire.

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