Intranasal delivery of pneumococcal polysaccharide vaccines

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/09 (2006.01) A61K 39/385 (2006.01) A61K 39/39 (2006.01) A61K 47/48 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2364442

The invention relates to a method for preventing against diseases induced by Streptococcus pneumoniae infections, which comprises mucosally administering to a patient in need of a S. pneumoniae capsular polysaccharide. This latter may be conjugated or not and is preferably mixed with a mucosal adjuvant such as cholera toxin, E. coli heatlabile toxin or RhinovaxTM. A preferred route of administration is the intranasal route.

L'invention concerne une méthode de prévention contre des maladies induites par des infections à streptococcus pneumoniae, laquelle consiste en une administration par la muqueuse à un patient nécessitant un polysaccharide capsulaire de S. pneumoniae. Ce dernier peut être conjugué ou non et il est de préférence mélangé à un adjuvant muqueux tel qu'une toxine de choléra, une toxine thermolabile de E. coli ou du Rhinovax?MC¿. Une voie d'administration préférée est la voie intranasale.

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