C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/28 (2006.01) A61K 9/00 (2006.01) A61K 39/395 (2006.01) C07K 16/30 (2006.01)
Patent
CA 2667466
The present invention relates to the intranasal delivery of therapeutic polypeptides and proteins comprising a Nanobody®, a domain antibody, a single domain antibody or a "dAb". The present invention provides compositions comprising a therapeutically effective amount of such polypeptide or protein and further comprising a pharmaceutically acceptable nasal carrier. The invention also relates to methods for the treatment of a subject comprising the delivery of said polypeptides and proteins to said subject by the nasal route.
La présente invention concerne l'administration intranasale de polypeptides et de protéines thérapeutiques comprenant un Nanobody®, un anticorps à domaine, un anticorps à domaine unique ou un 'dAb'. La présente invention concerne des compositions comprenant une quantité thérapeutiquement efficace d'un tel polypeptide ou d'une telle protéine et comprenant en outre un vecteur nasal pharmaceutiquement acceptable. L'invention concerne également des méthodes de traitement d'un sujet par administration desdits polypeptides et desdites protéines audit sujet par voie nasale.
Merchiers Pascal Gerard
Revets Hilde Adi Pierrette
Ablynx N.v.
Fetherstonhaugh & Co.
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