Intranasal influenza virus vaccine

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/00 (2006.01) A61K 39/39 (2006.01)

Patent

CA 2383105

The invention relates to the use of a non-live influenza virus antigen preparation, particularly a split influenza virus preparation, in the manufacture of a vaccine formulation for a one-dose intranasal vaccination against influenza, wherein the one-dose vaccination meets international regulatory requirements for influenza vaccines. Further provided are methods for the production of the vaccine, and a pharmaceutical kit comprising an intranasal administration device and the one-dose vaccine.

L'invention concerne l'utilisation d'une préparation d'antigène de virus grippaux non vivante, particulièrement une préparation anti-grippale sous-unitaire, dans la fabrication d'une formulation de vaccin pour une vaccination monodose intranasale contre la grippe, la monodose de vaccination répondant aux exigences réglementaires internationales pour les vaccins contre la grippe. L'invention concerne également des procédés pour la production de ce vaccin et un kit pharmaceutique comprenant un dispositif d'administration intranasale et ledit vaccin monodose.

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